On-Demand Fundamentals of MicroED

Explore the fundamentals of MicroED, a time saving technique in the toolbox of the synthetic chemist, and gain an appreciation for the theory, advantages, limitations, and applications of MicroED.

Pricing: Starting USD 158
Duration: 1–2 hours
Registration Info

About the Instructor(s)

Developed by the American Chemical Society with the help of leading experts in MicroED and electron crystallography.

Hosea M. Nelson, PhD  
Professor of Chemistry
Division of Chemistry and Chemical Engineering
California Institute of Technology

Brent Nannenga, PhD
Associate Professor
School for Engineering Matter, Transport and Energy
Arizona State University

Lee Joon Kim, PhD
Postdoctoral Fellow, Molecular Biophysics & Integrated Bioimaging (MBIB) Division
Lawrence Berkeley National Laboratory


Xiaodong Zou, PhD
Professor & Chair, Inorganic and Structural Chemistry Unit,
Deputy Head, Department of Materials and Environmental Chemistry
Stockholm University

Brian M. Stoltz, PhD
Victor and Elizabeth Atkins Professor of Chemistry
Investigator, Heritage Medical Research Institute
Division of Chemistry and Chemical Engineering
California Institute of Technology

About the Course

Microcrystal electron diffraction (MicroED) is a type of crystallography where small crystals can be used for structure determination. The technique has rapidly become a powerful tool for molecule structure characterization for synthetic chemists who are unable to grow crystals of a size suitable for X-ray diffraction. This course provides researchers with an understanding of the potential of this technique, including real-world examples, knowledge checks, links to additional resources, and assessments to ensure the information can be applied immediately in the lab.

What You Will Learn

  • Recognize the context of MicroED as a powerful tool in the toolkit of a synthetic chemist, including the unique advantages the technique offers
  • Understand the theory behind electron diffraction and electron crystallography while articulating the distinctions and similarities with X-ray diffraction/crystallography
  • Gain the ability to prepare a sample and acquire electron diffraction data
  • Learn the process and workflow for determination of a crystal structure by MicroED
  • Identify common statistical parameters encountered during data refinement and their connection to structure quality 

Who Should Attend

Researchers in academia, government, and industry who wish to gain an understanding about the use of MicroED and how it relates to other characterization techniques in terms of utility and complexity.

Course Outline

  • Agenda

    1. Introduction to MicroED
    2. Basics of Electron Crystallography    
    3. Performing MicroED Experiments
    4. Structural Accuracy, Rigor, and Statistics
    5. Appropriate Applications of MicroED and Preparing to Collaborate

Dates, Locations, and Prices



Early Bird Full Price
Member(Premium Package) $158
Member or Associate(Standard or Basic Package) $175
Non-Member $175