On-Demand Principles of Analytical Chemistry

Understand the science behind making chemical measurements.

Pricing: USD 199
Duration: 1–2 hours
Registration Info

About the Instructor(s)

Brian C. Smith
Founder and Principal, Spectros Associates

Brian C. Smith, Ph.D., is founder and Principal of Spectros Associates.

About the Course

An introduction to the science of making chemical measurements. Learn the fundamentals of information and sample gathering, measuring, and minimizing experimental error. We’ll cover the elementary statistics needed to understand chemical measurements, followed by proper use of calibrations.

Explore the principles of how chromatographs achieve chemical separations, which will help optimize your analyses.

Lastly, we’ll cover the principles of spectroscopy, which form the basis for understanding how FTIR and UV/Vis spectrometers identify and quantify molecules. Exercises and homework are used to increase the retention of knowledge.

  • Learn the three variables used to optimize analyses.
  • See how to quantify and minimize measurement error.
  • Learn how a chromatograph works and how to improve your separations.
  • Discover how infrared and UV/Vis spectrometers work and how to use them to solve industrial problems.

What You Will Learn

  • Advance your career by learning how to become a chemical problem solver.
  • See how to make your analyses faster, better, and cheaper.
  • Gain confidence in your use of chromatographs and spectrometers.

Who Should Attend

Anyone who works in a lab and makes chemical measurements of any type.

People who are new to making chemical measurements or who do not have formal training in analytical chemistry.

Managers and supervisors who need to understand better the measurements taking place in their labs will find this course a useful refresher.

Course Outline

  • Module 1

    What Is Analytical Chemistry?

    • Optimizing Analyses
    • Becoming a Problem Solver
    • Sampling
    • Significant Figures

    Quantifying Measurement Error

    • Random Error and Its Sources
      • Signal-to-Noise Ratios
      • Getting Rid of Noise
    • Systematic Error
    • Precision and Accuracy
  • Module 2

    Quantifying Measurement Error (continued)

    • Calibrations
      • Calibration Checks
      • Calibration Applicability

    Statistics for Chemical Measurement

    • Mode, Median, Mean
    • The Standard Deviation
    • Confidence Limits

    Introduction to Chromatography

    • Basic Theory
    • Modeling a Separation
  • Module 3

    Introduction to Chromatography (continued)

    • Peak Widths
    • Resolution
    • Optimizing Separations
    • Gas Chromatography (GC) 
    • High Pressure Liquid Chromatography (HPLC) 

    Principles of Spectroscopy

    • The Properties of Light
  • Module 4

    Principles of Spectroscopy (continued)

    • Fourier Transform Infrared Spectroscopy (FTIR)
      • Instrumentation
      • Sample Preparation: ATR
    • Ultraviolet-Visible (UV-Vis) Spectroscopy
      • Theory
      • Instrumentation

Dates, Locations, and Prices

On Demand course modules can be purchased a la carte for $199, each. All modules are held on a rolling basis throughout the year to accommodate your schedule and budget.


Early Bird Full Price
Member(Premium Package) $199
Member or Associate(Standard or Basic Package) $199
Non-Member $199

The registration fee includes seven days of access to the content, lecture slides (provided in PDF format), and email access to the instructor. Each person attending must register individually for this course.