Online Live Regulatory Toxicology for Chemists
Learn how to derive and evaluate toxicity information and how to apply that information to ensure compliance with regulations.
About the Instructor(s)
Owner, Tox&Ecotox Consulting
Dr. Philip Leber provides services to clients (industry, labs) in test design, chemical exposure evaluations, environmental impacts, and occupational safety. For many years, Dr. Leber has presented an ecological toxicity class and a general toxicity course for the American Chemical Society.
About the Course
Investigate chemical properties and exposure factors linked to adverse health conditions ranging from eye/skin irritation to allergic responses, birth defects, or cancer. Basic toxicology terminology and principles will be described, as well as the key regulations that are applicable in the handling, transportation, and use of chemical products.
General topics are:
- The discipline of toxicology and key regulations
- Chemical properties linked to toxic effect
- How to develop new toxicity and metabolism data
- Relevance of animal toxicity data to human health
- Classification of health hazards of chemicals
An introductory presentation will be available on the class website to acquaint participants with the field of ecological toxicology and chemical fate in the environment.
What You Will Learn
- Become familiar with concepts used in the toxicology field.
- Prepare yourself to actively participate in chemical development projects.
- Gain insights into data acquisition.
- Speak informatively on chemical safety and regulatory issues, and
- Learn how to communicate chemical safety to the general public.
Who Should Attend
Chemists, regulatory, and other technical professionals who are responsible for chemical safety, regulatory matters, and communications needed in employee safety, product stewardship, and product development.
Section 1: Overview
- Terminology & basic concepts
- Why is toxicology needed? Role of chemistry in toxicology
- Introduction to chemical regulations
Section 2: Chemical Exposures
- Sources of exposure
- Chemical properties & reactivity related to absorption
- Computer models of chemical properties
- Pharmaceuticals – FDA
Section 3: Metabolism of Chemicals
- Types of chemical biotransformations
- Metabolism & its impact on adverse effects
- FDA – Food packaging
Section 4: Toxicity Testing Methods
Developing new data
- Types of toxic endpoints with new test methods
- EPA – New chemical registrations
Section 5: Molecular Mechanisms of Action
- How chemicals induce adverse effects (e.g., liver damage, cancer)
- Data use in hazard classifications& regulations
- EPA – Air, water safety
Section 6: Risk Assessments
- Types of chemical risk evaluations
- Use of animal data to estimate human chemical risks
- Cancer vs. non-cancer risk estimations
- International regulations – European, Asian
Dates, Locations, and Prices
Five for four! Register five people for one course, one person for five courses, or any combination in between and your fifth registration is free. The free registration will be the course of the lowest price. Please note: This discount cannot be combined with any other discount offered.
Each person attending must register individually for this course.
Course fee includes electronic access to the course materials and session recordings.